Board Thread:LOC General Discussion/@comment-6053607-20130128172607/@comment-5706972-20130128205034

No, they don't. Only one skill of a type will activate in the same hit. NOTE: You have 5 cards, so you hit each Raid boss 5 times. You can have 3 cards with the same skill, and they can activate on 3 different hits, but will NEVER activate more than one per hit (and a MAXIMUM of 3 skills will activate in the entire attack).