Board Thread:LOC General Discussion/@comment-6053607-20130128172607/@comment-6100911-20130131180246

As of now, only a maximum of 3 skills can activate. Most of the time, at least one skill is guaranteed to go off. Another common occurrence is having two skills activate. You're really lucky if you get 3 skills up frequently as it will help a lot in battles. So the myth is busted. Skill activation is random except for the first card in your line-up